The Bio-Assembler
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The Bio-Assembler is as simple as 2D cell culturing and enables faster 3D cell culturing formation than any other 3D cell culturing product on the market. |
In The Works
| n3D is preparing to launch our 24-well version of the Bio-Assembler kit. Place a "pre-order" today by contacting us at info@n3dbio.com |
| Funding Glioblastoma Research | |
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3D CELL CULTURING - FAST & SIMPLE
Nano3D Biosciences (n3D) offers the Bio-Assembler, a unique cell culturing tool for any Life Science laboratory seeking three dimensional (3D) cell culturing solutions. n3D's breakthrough technology is easy to use, fast, scalable, scaffold-free, and avoids the use of basement membrane extract (BME), all in an in vivo like environment that promotes cell-cell interaction.
The Bio-Assembler™ uses
nanotechnology and magnetic levitation to provide the environment for cells to grow in 3D. This tool uses a biocompatible nanoparticle-assembly,
the Nanoshuttle, to gently deliver magnetic nanoparticles to cells. Designed
magnetic drives then levitate and bring cells together for rapid formation of 3D
cultures.
DID YOU KNOW?
When comparing 2D vs. 3D cell culturing, 3D cultures more closely recapitulate in vivo protein expression of N-cadherin in human glioblastoma cells. (Effect of 3D vs. 2D Cell Culture on Gene Expression and Protein Synthesis and Souza et al. Nature Nanotechnol. 2010)
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 Culturing Cancer Cells by Magnetic Levitation | Glioblastoma (GBM) is amongst the most common and most aggressive types of brain cancer. The above GBM cells (LN229) were cultured for 48 hours under magnetic levitation with the Bio-Assembler. The images above show brightfield (left) and GFP green fluorescence (right) photomicrographs of GFP expressing GBM cells. Our studies with other cell types also indicate that levitated cultures represent an improved in vitro cell culturing platform that can produce cells that recapitulate in vivo morphology, function, and protein expression. (Souza et al. Nature Nanotechnol. 2010)
How To... Levitate Cells with the Bio-Assembler.
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IMMUNOHISTOCHEMISTRY | Protein Expression
Detection of protein expression by immunohistochemistry is a sensitive and routine diagnostic of cell properties that probes cellular environment, function, differentiation, and cell-cell interactions. The images of GBM cells below show that the N-cadherin distribution (red stain) of levitated 3D cultures (middle) more accurately represents GBM grown in vivo (left) than when cultured in 2D (right). (Souza et al. Nature Nanotechnol. 2010)
How To... Perform Immunohistochemistry. |
| SPECIAL OFFERS | First Kit Discount
Save $200 on your First Kit (single well or 6-well)
Limited-time offer for first-time customers only. Purchase a Bio-Assembler Kit for only $100.00. Each additional kit is $300.00.
Save on Refills
Buy 2 and Get 3rd for $1.00
Purchase 2 Refills of Nanoshuttle and get the 3rd Refill for only $1.00 (nearly $200 savings). Each refill vial contains 600 ul of Nanoshuttle material, enough to treat three T-25 flasks.
Offer expires on 09/30/11.
Contact us at (713) 790-1833 or info@n3dbio.com to place an order. |
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