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Lab Life-Line

A Short Newsletter For The Busy Analytical Lab
From ACCTA, Inc.

"Analytical Solutions to Analytical Problems"
Vol. 8, No. 4A
Fourth Quarter, 2020

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What to Do When C18 Does or Doesn't Work

Oct 28 - 29, 2020

10:00 AM- 2:30 PM EST Each Day


The Eastern Analytical Symposium (EAS) is going virtual this year - everything is online - presentations, exhibits, and short courses.  Now you do not have to be at EAS to take an EAS Short Course! Discount prices for this course are available until Oct. 6. Register now!  And short course registration also gives you access to the entire EAS virtual event!

COURSE DESCRIPTION

Almost every LC lab operates in reversed-phase mode, but only a minority of users are taking advantage of the full capability in this separation technique. Troubleshooting problems is easier if you understand the technique, and tremendous improvements in selectivity, efficiency, and throughput are possible with only modest modifications. This one-day course, taught as two half-days, will provide an overview of the features that allow an RP application to succeed and answer the questions that most users have. Simple rules for improving your method can achieve dramatic results in reducing solvent usage and/or time, but only if you understand the rules and their limitations. Also, not every separation problem can be solved with a C18 column. If C18 does not work for you, we will show you what other options are available. Like all ACCTA courses, all discussions make extensive use of real-world case studies.

 

The full description is here: https://eas.org/2020/?page_id=6987

 

Registration Information is here: https://eas.org/2020/?page_id=5072


Have questions?  Contact us.
What We Have Been Doing During the Covid Quarantine (Case Study Snippets)

Stay-at-home orders and other quarantine restrictions have reduced the number of on-site visits, but we have still been busy.  Here are three successs stories all accomplished through remote consulting:

HPLC Method Development
We have been updating HPLC methods for a manufacturer of consumer products.  Our revised methods result in at least a 50 % reduction in analysis time, simpler and cheaper mobile phases, and streamlined sample preparation.  Initial methods are configured in ACCTA's method development laboratory, and then transferred electronically to the lab instruments.  We work directly with the lab staff to optimize the method and procedures for the local environment, and ensure that the transferred method demonstrates the required performance.

OpenLab Report Template Development
A pharmaceutical contract laboratory needed an automated report to perform some special impurity calculations.  Their current method required manual transcription of data to an external spreadsheet.  ACCTA developed a template that automatically processed the chromatographic data, applied different relative response factors for each known impurity, and summarized the results in a single report along with other QC calculations.  Local staff were then trained via webinar on how to use the template and make future modifications if necessary.

HPLC Sugar Method Adapted
A well-known food manufacturer needed a revised method to report a different set of small sugars.  ACCTA worked remotely via phone, email, and webinar to help the lab staff update their existing methodology.

Maybe we can help you too!  Remote consulting can be flexible and more responsive to your needs and schedule, and the costs are less since there are no travel costs.  Contact us now before our schedule fills up.
Thought For The Day

[We normally select a single quote, but in the current situation it seemed like these quotes all had some relevance.]

"God invented time so everything wouldn't happen all at once."

– Woody Allen 

 

"The point is that in the past the time-span of important change was considerably longer than that of a single human life. Thus mankind was trained to adapt itself to fixed conditions. Today the time-span is considerably shorter than that of human life, and accordingly our training must prepare individuals to face a novelty of conditions."

– A. N. Whitehead,

Adventures of Ideas 

 

"It is better to ask some of the questions than to know all the answers."

– James Thurber (1894-1961),

"The Scotty Who Knew Too Much,"

Fables for Our Time: and Famous Poems Illustrated, 1939 

 

"The superior man, when he sees what is good, moves toward it; and when he sees his errors, he turns away from them."

– The Book of Changes,

Appendix II, Hexagram 42,

China, c. 1200 B.C., J. Legge, Trans. 

 

Public Events

General

Introduction to HPLC
May 2021
Chicago, IL


Watch here for updates on the next session of this popular course.


Vendor

HPLC with OpenLab (v 2.4) - 4 days

10-13 November 2020

This hands-on course offers a complete overview of essential operations with this CDS software.  Very helpful for users at all levels.

Download Center
Jump start your method development with our Column Screening Service

Download our Pittcon presentation on "Improved Options for Sugar Analysis"

Downloae our Pittcon poster on "Use Your Autosampler to Make Calibration Standards"

D
ownload the flyer for Practical Guide To Reversed Phase LC

Download the flyer for Secrets of OpenLab 2

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Contact Details:
Merlin K. L. Bicking, Ph. D.
Senior Analytical Scientist and President
Phone: +1 (651) 731-3670
Email: info@accta.com
This message was sent to info@accta.com by info@accta.com
3534 Jessie Ct, St. Paul, MN, 55125


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