Help Lower Your Risk for Prostate Cancer
CHI HEALTH LETTER July 31, 2015
Featured Story: Lupron is not the best solution

A well-built truck driver in his 60s was diagnosed with prostate cancer and his PSA was at 17. His doctor began giving him Lupron injections (synthetic gonadotropin releasing hormone to treat prostate cancer symptoms):
  • 1st Lupron shot: His PSA dropped to 2.5
  • 2nd Lupron shot: His PSA dropped to 1.5
  • 3rd Lupron shot: His prostate cancer was no longer improving
Lupron has been an effective drug for prostate cancer for many years, but sometimes it is still not enough. As in this case, there was no longer any improvement after the 3rd shot. Lupron also causes many undesirable side effects such as impotence, reduced sexual interest, depression, and more.

So his doctor then put him on Avodart and Terazosin (5-alpha reductase inhibitor drugs) but these yielded no results because these drugs only help manage BPH and Prostatitis, not prostate cancer. The truck driver wanted to get better so he then recently consulted Dr. Chi and was recommended to take Angiostop, Revivin, and Myomin.

Drugs should not be your only approach for prostate cancer. There are other ways to help manage the problem, first of which is preventing prostate cancer. You can do this by determining your risk and taking preventative measures as early as possible.

According to Dr. William Li, MD, studies found that 50% of men between 50 and 60 years old already have microscopic prostate tumors (TED Convention. “Can we eat to starve cancer?” Feb. 2010). Dr. Li is a Harvard graduate and clinically trained in Internal Medicine at the Massachusetts General Hospital in Boston. He founded the Angiogenesis Foundation and spent many years researching ways to fight cancer. Based on the studies, this means that by the time men reach 80, they already have an 80% chance of getting prostate cancer!

It is therefore vital to know early warning signs of prostate cancer so steps can be taken to keep it from getting worse. Strawberry dots on the tongue or cherry angiomas on the torso (Figures 1 and 2) are early markers of estrogen dominance, which increases a man’s risk for prostate cancer. Once you see these, you can start taking Myomin to reduce excess estrogen.












In order to evaluate your risk for prostate cancer, you should also monitor your PSA (Prostate Specific Antigen) levels. Clinically, doctors only take action when your PSA levels are at around 4. Even at this point the doctor will probably recommend a watch-and-wait period of about 6 months to check your PSA again or have biopsy. Do not wait until your PSA is high or until a biopsy is required to take action. At the earliest signs, start addressing your prostate problems.

PSA Test for Prostate Cancer

At the ACAM (American College for Advancement in Medicine) in November 2002, Ronald Wheeler, MD, a prostate specialist from FL, reported that men in their 40s (49 years and younger) who have PSA levels greater than 0.7 may already have prostate cancer. The following year, at the Annual Cancer Control Convention in Los Angeles, he reiterated that recurring prostatitis causes prostate cancer when PSA levels exceed 1.

But the current PSA threshold is much higher at 4.0 ng/mL. At this point, many doctors would usually recommend a biopsy to detect prostate cancer. However, many researchers have been recommending the need to lower this threshold to 2.5 ng/mL for earlier detection of prostate cancer and biopsy screening. Even with biopsy screening though, there are still missed occurrences. Biopsy misses 82% of prostate cancer cases in men under 60 years old with PSA levels over 2.6 (Table 1). In men over 60 with a PSA of over 2.6, the rate of missed occurrence is at 65% (New England Journal of Medicine. 2004; 350(22): 2239-46; NEJM. 2003; 349:335-42; Patient Care. Dec 2003). So men should not wait until their PSA reaches 4 or even 2.5 before taking action. Just like Dr. Wheeler suggested, prostate cancer may already be present at PSA levels greater than 0.7. If biopsy is recommended, take Angiostop a month before the procedure to lower the risk of recurrence if prostate cancer is indeed present.









Studies published in the British Medical Journal on April 15, 2013 further confirmed that a PSA level even under 1 is already associated with prostate cancer. Here is what they found.

Men that fit in these categories should not rule out their chance for metastatic prostate cancer:
  • Age 45 - 49 with PSA> 0.68
  • Age 51 – 55 with PSA> 0.85
This means that men in this age range should not disregard PSA levels of over 0.68 or 0.85. If no preventative action is taken, then this might eventually develop into prostate cancer.

Furthermore, men in the following categories have a very high mortality rate caused by prostate cancer:
  • Age 45 – 49 with PSA> 1.6
  • Age 51 – 55 with PSA> 2.4
So if men who fall into these categories do not address the issue, then there is a high risk of them dying from prostate cancer.
Many Men Do Not Know that They have High Prostate Cancer risk

C.D., 45-year-old male from FL, had strawberry dots on his tongue, low testosterone and a PSA level of 1.3 in February 2009 (Table 2). Unaware that he was already at risk for prostate cancer (At 44 years old, his PSA should be <0.68), he started taking the supplements below in hopes of increasing his testosterone. The following year, his testosterone remained below normal range at 293 (normal is>600) despite the supplements, while his PSA level increased to 1.8 (at 45 years old, a PSA over 1.6 puts him at increased risk of dying from prostate cancer).
  • DHEA (10mg/day) – precursor hormone to Testosterone
  • Tribulus (338mg QID) - herb supplement for increased Testosterone
  • DIM (100mg/day) – recommended when Estrone (E1) is already elevated, to adjust 2/16 hydroxyestrone ratio
  • Doxazosin (BPH drug) - 5- α reductase inhibitor
  • Stinging Nettle Root (300mg BID) – herb supplement for prostate
  • Zinc (55mg/day)







He was supplementing with DHEA, which he didn’t really need at his age. With DHEA, his testosterone should have increased but it didn’t because it was being converted to Estrone (E1) and Estradiol (E2). Looking at Chart 1, DHEA can further convert to Estrone ( DHEA -> Androstenedione -> Estrone[E1]) or to Estradiol ( DHEA -> Androstenedione -> Testosterone -> Estradiol [E2]). Taking DHEA is fine as long as he stops this conversion to E1 and E2. He can achieve this and increase his testosterone by taking Myomin to stop the aromatization to E1 and E2. But he instead took DIM with the intention of inhibiting the estrogen increase, but DIM acts too late in the hormonal pathway.



















He was also taking Doxazosin which inhibits the 5- α reductase enzyme that converts Testosterone into DHT, but it could be too potent. Completely inhibiting the 5- α reductase enzyme could cause estrogen dominance because inhibiting the Testosterone -> DHT conversion means there is more Testosterone being converted to Estradiol. It can also cause other issues such as gynecomastia (more details in the 7/24/2015 issue of the Chi Health Letter). Prosta Chi is a better alternative, since it only partially inhibits the 5- α reductase enzyme.


Men on BHRT or taking supplements to increase testosterone are at an increased risk for prostate cancer, so it is very important to monitor estrogen and PSA levels (more information in 12/ 12/2014 issue of the Chi Health Letter). In C.D.’s case, taking Myomin and Prosta Chi together would help him increase his testosterone while keeping his estrogen and PSA level under control.

Increased Estradiol (E2) and Estrone (E1) Linked to Increasing PSA Levels

For men, increased levels of the harmful estrogens, Estradiol (E2) and Estrone (E1), can cause elevated PSA. You can reduce your estrogens by inhibiting the aromatase enzyme that converts Testosterone to Estradiol and Androstenedione to Estrone (Chart 1). The natural herbal supplement, Myomin, reduces the DNA expression of the aromatase enzyme that, in turn, reduces Estradiol (E2) and Estrone (E1) levels. Men who are supplementing with DHEA, pregnenolone, or testosterone should add Myomin to reduce their conversion to E1 and E2 as well as to manage PSA level.

When inhibiting the conversion of Testosterone into Estradiol, whether with supplements or drugs, it is recommended to also inhibit the 5- α reductase enzyme, which converts testosterone into DHT (Chart 1). This is because your testosterone levels can build up and convert excessively into DHT. DHT is a substrate of testosterone responsible for BPH (enlarged prostate) and prostatitis. Prosta Chi is recommended to partially inhibit the 5- α reductase enzyme and reduce DHT levels. Take Myomin with Prosta Chi for prostate issues.


Recommended for Prostate Cancer

  • MYOMIN – Reduces PSA levels by reducing both Estradiol (E2) and Estrone (E1) levels.
  • PROSTA CHI – Helps improve prostate conditions by reducing the excess conversion of Testosterone to DHT.
  • ANGIOSTOP – Helps prevent the growth and spread of prostate cancer by inhibiting the growth factors necessary for prostate cancer to survive. If PSA is high for your age, you have to use Angiostop with Myomin.
    • It inhibits angiogenesis (the formation of new blood vessels) in cancers.
    • Prostate cancer requires the growth factors VEGFR, PDGFR, EGFR, and FGFR to grow. Angiostop blocks all these growth factors.
  • REVIVIN – Works together with Angiostop to manage the growth of cancers.Inhibits the uncontrolled cell replication of cancer by blocking the transition from the G1 phase to the S phase.
Prostate Cancer Cases

K. Greenawalt, DC, has a 59-year-old patient with prostatic epithelial hyperplasia (not cancer yet). His PSA levels were dangerously high at 12 (Table 3). He began taking Angiostop, Myomin, Revivin and Kidney Chi. After 6 months, his PSA dropped to 6 and After 1 year, his PSA dropped significantly down to 3.06!







M. Guevara, MD from CA, has a 50-year-old patient with prostate cancer. His PSA level was at a very high 6.1 in September 2013. He began taking Angiostop, Revivin, Myomin, and Prosta Chi (3 TID each) in March 2014. After 7 months of consistently taking the supplements, his PSA reduced significantly to 4.4 (Table 4).









In 2008, J. Weber, DC, DCBCN, from NY, had a 55-year-old patient with prostate cancer. After taking Myomin (3 TID) and Angiostop (3 TID) for 4 months, his PSA levels reduced from 4.69 to 3.3 (Table 5). An ultrasound and a digital rectal exam found no sign of the tumor!








S. Downs, MD from CA, had an 80-year-old patient who was treated for prostate cancer and was declared cancer free. His PSA levels were still high so he was given Avodart (dutasteride) to try to manage it. After a year on Avodart, his estradiol and PSA were still elevated. He began taking Myomin (3 BID) and Prosta Chi (3 BID), and after 3 months both his Estradiol and PSA levels dropped. Dr. Downs was skeptical with these herbal supplements so he took him off them, but his PSA and Estradiol rose again. Dr. Downs then said he can go back on the supplements, and his PSA and Estradiol have leveled back down to 3.6 (see Table 6). He was continuously taking Avodart, but in conjunction with Myomin and Prosta Chi he was able to better manage his PSA and Estradiol levels.





C. Andonian, ND from MO, has a 69-year-old patient with prostate cancer. He is 5’8”, weighs 275 lbs and has cherry angiomas on the torso as well as gynecomastia. In January, his PSA was at 10.1. He began taking Angiostop, Myomin, Revivin, Asparagus Extract and Reishi Spore Extract (3 TID each). After 6 months, his PSA dropped sharply to 4.99 (Table 7).







R. Ornelas, DC from CA, has a 40-year-old patient who had prostate cancer for 5 years. He had a prostatectomy to remove the cancer, then underwent chemotherapy and radiation to prevent the cancer from returning. On January 2015, a test detected that he still had some detectable levels of PSA when it should be 0. Dr. Ornelas then recommended Angiostop, Revivin, Myomin, Asparagus Extract and Reishi Spore Extract (3 TID each). After 3 months on the protocol (July 2015), he had another test and his PSA was not detectable.


Summary

  • Elevated Prostate-Specific Antigen (PSA) levels may indicate prostate issues such as BPH, Prostatitis, or even Prostate Cancer.
  • Men who have strawberry dots on the tongue or cherry angiomas on the torso (Figures 1 and 2) are estrogen dominant and are, therefore, at an increased risk for prostate issues.
  • For Men under the age of 50, PSA should be less than 0.68
  • For Men under the age of 55, PSA should be less than 0.85
  • Dr. Chi recommends that men older than 60 should keep their PSA under 1; men over 70 years old should not have a PSA over 2.5. Furthermore, men should not have serum Estradiol levels over 30.
  • It is best to monitor your PSA levels in order to determine your risk for prostate cancer earlier and then take the necessary precautionary measures.
  • Men can use Myomin to reduce Estradiol (E2) and Estrone (E1), in turn reducing PSA levels.
  • Men can use Prosta Chi to reduce DHT levels and improve prostate conditions. High DHT levels are linked to BPH, Prostatitis, and hair loss.
  • Men on BHRT or taking supplements to increase testosterone should take Myomin and Prosta Chi to manage PSA and Estradiol levels.
  • Angiostop, an extract of sea cucumber, is an angiogenesis inhibitor that can be taken with Myomin to help prevent the growth of prostate cancer. Revivin may also be added to manage cancer growth. If prostate biopsy is recommended, take Angiostop one month prior to the procedure

Diet and Lifestyle Advice:

  • Sitting down for long periods of time and holding your urine for too long can cause prostate issues.
  • Driving or bicycling on bumpy roads for long durations could also cause prostate issues.
  • Dr. Chi recommends avoiding estrogenic foods, soy, flaxseed, alfalfa, and fatty foods. For those who eat meat, grass fed meat is recommended.
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